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Influence of point mutations on the stability, dimerization, and oligomerization of human cystatin C and its L68Q variant

Human cystatin C (hCC) is a small but very intriguing protein. Produced by all nucleated cells is found in almost all tissues and body fluids where, at physiological conditions, plays a role of a very potent inhibitor of cysteine proteases. Biologically active hCC is a monomeric protein but during c...

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Detalles Bibliográficos
Autores principales:	Szymańska, Aneta, Jankowska, Elżbieta, Orlikowska, Marta, Behrendt, Izabela, Czaplewska, Paulina, Rodziewicz-Motowidło, Sylwia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2012
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406405/ https://www.ncbi.nlm.nih.gov/pubmed/22866027 http://dx.doi.org/10.3389/fnmol.2012.00082

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