Caspase-1: is IL-1 just the tip of the ICEberg?

Caspase-1, formerly known as interleukin (IL)-1-converting enzyme is best established as the protease responsible for the processing of the key pro-inflammatory cytokine IL-1β from an inactive precursor to an active, secreted molecule. Thus, caspase-1 is regarded as a key mediator of inflammatory pr...

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Detalles Bibliográficos
Autores principales: Denes, A, Lopez-Castejon, G, Brough, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406585/
https://www.ncbi.nlm.nih.gov/pubmed/22764097
http://dx.doi.org/10.1038/cddis.2012.86

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