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Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity

According to the concept of lipotoxicity, ectopic accumulation of lipids in non-adipose tissue induces pathological changes. The most prominent effects are seen in fatty liver disease, lipid cardiomyopathy, non-insulin-dependent diabetes mellitus, insulin resistance and skeletal muscle myopathy. We...

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Detalles Bibliográficos
Autores principales: Tamilarasan, K P, Temmel, H, Das, S K, Al Zoughbi, W, Schauer, S, Vesely, P W, Hoefler, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406590/
https://www.ncbi.nlm.nih.gov/pubmed/22825472
http://dx.doi.org/10.1038/cddis.2012.91