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The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase
CLECSF8 is a poorly characterized member of the “Dectin-2 cluster” of C-type lectin receptors and was originally thought to be expressed exclusively by macrophages. We show here that CLECSF8 is primarily expressed by peripheral blood neutrophils and monocytes and weakly by several subsets of periphe...
Autores principales: | Graham, Lisa M., Gupta, Vandana, Schafer, Georgia, Reid, Delyth M., Kimberg, Matti, Dennehy, Kevin M., Hornsell, William G., Guler, Reto, Campanero-Rhodes, Maria A., Palma, Angelina S., Feizi, Ten, Kim, Stella K., Sobieszczuk, Peter, Willment, Janet A., Brown, Gordon D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406680/ https://www.ncbi.nlm.nih.gov/pubmed/22689578 http://dx.doi.org/10.1074/jbc.M112.384164 |
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