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Genetic divergence and the genetic architecture of complex traits in chromosome substitution strains of mice

BACKGROUND: The genetic architecture of complex traits strongly influences the consequences of inherited mutations, genetic engineering, environmental and genetic perturbations, and natural and artificial selection. But because most studies are under-powered, the picture of complex traits is often i...

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Detalles Bibliográficos
Autores principales: Spiezio, Sabrina H, Takada, Toyoyuki, Shiroishi, Toshihiko, Nadeau, Joseph H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3406986/
https://www.ncbi.nlm.nih.gov/pubmed/22606935
http://dx.doi.org/10.1186/1471-2156-13-38