Milnacipran inhibits glutamatergic N-Methyl-D-Aspartate receptor activity in Spinal Dorsal Horn Neurons

BACKGROUND: Antidepressants, which are widely used for treatment of chronic pain, are thought to have antinociceptive effects by blockade of serotonin and noradrenaline reuptake. However, these drugs also interact with various receptors such as excitatory glutamatergic receptors. Thermal hyperalgesi...

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Detalles Bibliográficos
Autores principales: Kohno, Tatsuro, Kimura, Masafumi, Sasaki, Mika, Obata, Hideaki, Amaya, Fumimasa, Saito, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407012/
https://www.ncbi.nlm.nih.gov/pubmed/22716121
http://dx.doi.org/10.1186/1744-8069-8-45

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