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NMR Structure of Hsp12, a Protein Induced by and Required for Dietary Restriction-Induced Lifespan Extension in Yeast

Dietary restriction (DR) extends lifespan in yeast, worms, flies and mammals, suggesting that it may act via conserved processes. However, the downstream mechanisms by which DR increases lifespan remain unclear. We used a gel based proteomic strategy to identify proteins whose expression was induced...

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Detalles Bibliográficos
Autores principales: Herbert, Andrew P., Riesen, Michèle, Bloxam, Leanne, Kosmidou, Effie, Wareing, Brian M., Johnson, James R., Phelan, Marie M., Pennington, Stephen R., Lian, Lu-Yun, Morgan, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407059/
https://www.ncbi.nlm.nih.gov/pubmed/22848679
http://dx.doi.org/10.1371/journal.pone.0041975