HILI Inhibits TGF-β Signaling by Interacting with Hsp90 and Promoting TβR Degradation

PIWIL2, called HILI in humans, is a member of the PIWI subfamily. This subfamily has highly conserved PAZ and Piwi domains and is implicated in several critical functions, including embryonic development, stem-cell self-renewal, RNA silencing, and translational control. However, the underlying molec...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Kun, Lu, Yilu, Yang, Ping, Li, Chao, Sun, Huaqin, Tao, Dachang, Liu, Yunqiang, Zhang, Sizhong, Ma, Yongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407066/
https://www.ncbi.nlm.nih.gov/pubmed/22848678
http://dx.doi.org/10.1371/journal.pone.0041973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407066/
https://www.ncbi.nlm.nih.gov/pubmed/22848678
http://dx.doi.org/10.1371/journal.pone.0041973

Ejemplares similares