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PAK1 Kinase Promotes Cell Motility and Invasiveness through CRK-II Serine Phosphorylation in Non-Small Cell Lung Cancer Cells

The role of c-Crk (CRK) in promoting metastasis is well described however the role of CRK phosphorylation and the corresponding signaling events are not well explained. We have observed CRK-II serine 41 phosphorylation is inversely correlated with p120-catenin and E-cadherin expressions in non-small...

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Detalles Bibliográficos
Autores principales: Rettig, Matthew, Trinidad, Kenny, Pezeshkpour, G., Frost, Patrick, Sharma, Sherven, Moatamed, Farhad, Tamanoi, Fuyuhiko, Mortazavi, Fariborz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407072/
https://www.ncbi.nlm.nih.gov/pubmed/22848689
http://dx.doi.org/10.1371/journal.pone.0042012

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