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Kinetic and Dynamic Computational Model-Based Characterization of New Proteins in Mice: Application to Interferon Alpha Linked to Apolipoprotein A-I
Interferon alpha linked to apolipoprotein A-I has been recently proposed as an improved interferon-based therapy. In the present study, we aimed to develop a computational model to gain further insight into the in vivo behaviour of this new fusion protein. In order to facilitate in vivo evaluation o...
Autores principales: | Parra-Guillen, Zinnia Patricia, Fioravanti, Jessica, Medina-Echeverz, Jose, Gomar, Celia, Ardaiz, Nuria, Troconiz, Iñaki F., Berraondo, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407104/ https://www.ncbi.nlm.nih.gov/pubmed/22848716 http://dx.doi.org/10.1371/journal.pone.0042100 |
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