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Ribavirin Exerts Differential Effects on Functions of Cd4(+) Th1, Th2, and Regulatory T Cell Clones in Hepatitis C
Ribavirin improves outcomes of therapy in chronic hepatitis C but its mode of action has still remained unclear. Since ribavirin has been proposed to modulate the host’s T cell responses, we studied its direct effects on CD4(+) T cell clones with diverse functional polarization which had been genera...
Autores principales: | Langhans, Bettina, Nischalke, Hans Dieter, Arndt, Simone, Braunschweiger, Ingrid, Nattermann, Jacob, Sauerbruch, Tilman, Spengler, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407113/ https://www.ncbi.nlm.nih.gov/pubmed/22848715 http://dx.doi.org/10.1371/journal.pone.0042094 |
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