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Age-Associated Changes In Oxidative Stress and NAD(+) Metabolism In Human Tissue
Nicotinamide adenine dinucleotide (NAD(+)) is an essential electron transporter in mitochondrial respiration and oxidative phosphorylation. In genomic DNA, NAD(+) also represents the sole substrate for the nuclear repair enzyme, poly(ADP-ribose) polymerase (PARP) and the sirtuin family of NAD-depend...
Autores principales: | Massudi, Hassina, Grant, Ross, Braidy, Nady, Guest, Jade, Farnsworth, Bruce, Guillemin, Gilles J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407129/ https://www.ncbi.nlm.nih.gov/pubmed/22848760 http://dx.doi.org/10.1371/journal.pone.0042357 |
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