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Fbxw7 Controls Angiogenesis by Regulating Endothelial Notch Activity

Notch signaling controls fundamental aspects of angiogenic blood vessel growth including the selection of sprouting tip cells, endothelial proliferation and arterial differentiation. The E3 ubiquitin ligase Fbxw7 is part of the SCF protein complex responsible for the polyubiquitination and thereby p...

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Detalles Bibliográficos
Autores principales:	Izumi, Nanae, Helker, Christian, Ehling, Manuel, Behrens, Axel, Herzog, Wiebke, Adams, Ralf H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407154/ https://www.ncbi.nlm.nih.gov/pubmed/22848434 http://dx.doi.org/10.1371/journal.pone.0041116

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