Cargando…

Viral Reverse Transcriptases Show Selective High Affinity Binding to DNA-DNA Primer-Templates that Resemble the Polypurine Tract

Previous results using a SELEX (Systematic Evolution of Ligands by Exponential Enrichment)-based approach that selected DNA primer-template duplexes binding with high affinity to HIV reverse transcriptase (RT) showed that primers mimicking the 3′ end, and in particular the six nt terminal G tract, o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nair, Gauri R., Dash, Chandravanu, Le Grice, Stuart F. J., DeStefano, Jeffrey J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407194/ https://www.ncbi.nlm.nih.gov/pubmed/22848574 http://dx.doi.org/10.1371/journal.pone.0041712

Ejemplares similares

Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase
por: Figiel, Małgorzata, et al.
Publicado: (2018)

Examining the ribonuclease H primer grip of HIV-1 reverse transcriptase by charge neutralization of RNA/DNA hybrids
por: Dash, Chandravanu, et al.
Publicado: (2008)

Selection of primer-template sequences that bind human immunodeficiency virus reverse transcriptase with high affinity
por: DeStefano, Jeffrey J., et al.
Publicado: (2006)

Purine analog substitution of the HIV-1 polypurine tract primer defines regions controlling initiation of plus-strand DNA synthesis
por: Rausch, Jason W., et al.
Publicado: (2007)

Effects of HIV-1 reverse transcriptase connection subdomain mutations on polypurine tract removal and initiation of (+)-strand DNA synthesis
por: Betancor, Gilberto, et al.
Publicado: (2015)

Selection of Primer–Template Sequences That Bind with Enhanced Affinity to Vaccinia Virus E9 DNA Polymerase
por: DeStefano, Jeffrey J., et al.
Publicado: (2022)

Structural probing of the HIV-1 polypurine tract RNA:DNA hybrid using classic nucleic acid ligands
por: Turner, Kevin B., et al.
Publicado: (2008)

Ty3 reverse transcriptase complexed with an RNA/DNA hybrid shows structural and functional asymmetry
por: Bona, Marion, et al.
Publicado: (2013)

Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function
por: Mandal, Dibyakanti, et al.
Publicado: (2006)

Interactions between HIV-1 Reverse Transcriptase and the Downstream Template Strand in Stable Complexes with Primer-Template
por: Rutvisuttinunt, Wiriya, et al.
Publicado: (2008)

Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry
por: Nowak, Elżbieta, et al.
Publicado: (2014)

Integrative structural biology studies of HIV-1 reverse transcriptase binding to a high-affinity DNA aptamer
por: Tuske, Steve, et al.
Publicado: (2020)

Duplex structural differences and not 2′-hydroxyls explain the more stable binding of HIV-reverse transcriptase to RNA-DNA versus DNA-DNA
por: Olimpo, Jeffrey T., et al.
Publicado: (2010)

SiRNA-Induced Mutation in HIV-1 Polypurine Tract Region and Its Influence on Viral Fitness
por: Rausch, Jason W., et al.
Publicado: (2015)

Targeting MYC Regulation with Polypurine Reverse Hoogsteen Oligonucleotides
por: Valiuska, Simonas, et al.
Publicado: (2022)

Human DNA polymerase α in binary complex with a DNA:DNA template-primer
por: Coloma, Javier, et al.
Publicado: (2016)

Targeting KRAS Regulation with PolyPurine Reverse Hoogsteen Oligonucleotides
por: Psaras, Alexandra Maria, et al.
Publicado: (2022)

Selection of 2′-deoxy-2′-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinity
por: Alves Ferreira-Bravo, Irani, et al.
Publicado: (2015)

Novel mutations in Moloney Murine Leukemia Virus reverse transcriptase increase thermostability through tighter binding to template-primer
por: Arezi, Bahram, et al.
Publicado: (2009)

Reverse transcriptases prime DNA synthesis
por: Zabrady, Matej, et al.
Publicado: (2023)

Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid
por: Nowak, Elżbieta, et al.
Publicado: (2013)

Enzymatic Primer-Extension with Glycerol-Nucleoside Triphosphates on DNA Templates
por: Chen, Jesse J., et al.
Publicado: (2009)

Facile single-stranded DNA sequencing of human plasma DNA via thermostable group II intron reverse transcriptase template switching
por: Wu, Douglas C., et al.
Publicado: (2017)

Phosphoryl guanidine oligonucleotides as primers for RNA-dependent DNA synthesis using murine leukemia virus reverse transcriptase
por: Dyudeeva, E.S., et al.
Publicado: (2022)

Unwinding of primer-templates by archaeal family-B DNA polymerases in response to template-strand uracil
por: Richardson, Tomas T., et al.
Publicado: (2013)

SJP-L-5 inhibits HIV-1 polypurine tract primed plus-strand DNA elongation, indicating viral DNA synthesis initiation at multiple sites under drug pressure
por: Zhang, Xing-Jie, et al.
Publicado: (2018)

Functional roles of carboxylate residues comprising the DNA polymerase active site triad of Ty3 reverse transcriptase
por: Bibillo, Arkadiusz, et al.
Publicado: (2005)

Downstream Oligonucleotides Strongly Enhance the Affinity of GMP to RNA Primer–Template Complexes
por: Tam, Chun Pong, et al.
Publicado: (2017)

Author Correction: Facile single-stranded DNA sequencing of human plasma DNA via thermostable group II intron reverse transcriptase template switching
por: Wu, Douglas C., et al.
Publicado: (2018)

PolyPurine Reverse Hoogsteen Hairpins Work as RNA Species for Gene Silencing
por: Aubets, Eva, et al.
Publicado: (2021)

Abolishing HIV-1 infectivity using a polypurine tract-specific G-quadruplex-forming oligonucleotide
por: Voges, Maike, et al.
Publicado: (2016)

Separable structural requirements for cDNA synthesis, nontemplated extension, and template jumping by a non-LTR retroelement reverse transcriptase
por: Pimentel, Sydney C., et al.
Publicado: (2022)

Novel insights from structural analysis of lentiviral and gammaretroviral reverse transcriptases in complex with RNA/DNA hybrids
por: Le Grice, Stuart, et al.
Publicado: (2013)

Correction of the aprt Gene Using Repair-Polypurine Reverse Hoogsteen Hairpins in Mammalian Cells
por: Félix, Alex J., et al.
Publicado: (2019)

Gene Correction of Point Mutations Using PolyPurine Reverse Hoogsteen Hairpins Technology
por: Félix, Alex J., et al.
Publicado: (2020)

INSTIs and NNRTIs Potently Inhibit HIV-1 Polypurine Tract Mutants in a Single Round Infection Assay
por: Smith, Steven J., et al.
Publicado: (2021)

Template-switching artifacts resemble alternative polyadenylation
por: Balázs, Zsolt, et al.
Publicado: (2019)

DNA models of trinucleotide frameshift deletions: the formation of loops and bulges at the primer–template junction
por: Baase, Walter A., et al.
Publicado: (2009)

The Emerging Role of Telomerase Reverse Transcriptase in Mitochondrial DNA Metabolism
por: Gordon, Donna M., et al.
Publicado: (2010)

Limited reverse transcriptase activity of phi29 DNA polymerase
por: Krzywkowski, Tomasz, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3bn2jqmmv7qen4kj0kmqi3jq4i