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Genome-Wide Histone Acetylation Is Altered in a Transgenic Mouse Model of Huntington's Disease

In Huntington's disease (HD; MIM ID #143100), a fatal neurodegenerative disorder, transcriptional dysregulation is a key pathogenic feature. Histone modifications are altered in multiple cellular and animal models of HD suggesting a potential mechanism for the observed changes in transcriptiona...

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Detalles Bibliográficos
Autores principales:	McFarland, Karen N., Das, Sudeshna, Sun, Ting Ting, Leyfer, Dmitri, Xia, Eva, Sangrey, Gavin R., Kuhn, Alexandre, Luthi-Carter, Ruth, Clark, Timothy W., Sadri-Vakili, Ghazaleh, Cha, Jang-Ho J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407195/ https://www.ncbi.nlm.nih.gov/pubmed/22848491 http://dx.doi.org/10.1371/journal.pone.0041423

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