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PDHK-2 Deficiency Is Associated with Attenuation of Lipase-Mediated Fat Consumption for the Increased Survival of Caenorhabditis elegans Dauers

In Caenorhabditis elegans, slow fat consumption has been suggested to contribute to the extension of the survival rate during nutritionally adverse conditions. Here, we investigated the potential role of pyruvate dehydrogenase kinase (PDHK)-2, the C. elegans homolog of mammalian PDK, effects on fat...

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Detalles Bibliográficos
Autores principales: Kim, Sunhee, Shin, E-Jin, Hahm, Jeong-Hoon, Park, Pil-Jong, Hwang, Ji-Eun, Paik, Young-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407204/
https://www.ncbi.nlm.nih.gov/pubmed/22848591
http://dx.doi.org/10.1371/journal.pone.0041755