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Streptococcus pyogenes SpyCEP Influences Host-Pathogen Interactions during Infection in a Murine Air Pouch Model

Streptococcus pyogenes is a major human pathogen worldwide, responsible for both local and systemic infections. These bacteria express the subtilisin-like protease SpyCEP which cleaves human IL-8 and related chemokines. We show that localization of SpyCEP is growth-phase and strain dependent. Signif...

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Detalles Bibliográficos
Autores principales: Chiappini, Nico, Seubert, Anja, Telford, John L., Grandi, Guido, Serruto, Davide, Margarit, Immaculada, Janulczyk, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407228/
https://www.ncbi.nlm.nih.gov/pubmed/22848376
http://dx.doi.org/10.1371/journal.pone.0040411