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Streptococcus pyogenes SpyCEP Influences Host-Pathogen Interactions during Infection in a Murine Air Pouch Model
Streptococcus pyogenes is a major human pathogen worldwide, responsible for both local and systemic infections. These bacteria express the subtilisin-like protease SpyCEP which cleaves human IL-8 and related chemokines. We show that localization of SpyCEP is growth-phase and strain dependent. Signif...
Autores principales: | Chiappini, Nico, Seubert, Anja, Telford, John L., Grandi, Guido, Serruto, Davide, Margarit, Immaculada, Janulczyk, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407228/ https://www.ncbi.nlm.nih.gov/pubmed/22848376 http://dx.doi.org/10.1371/journal.pone.0040411 |
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