Cargando…

Leptin action on nonneuronal cells in the CNS: potential clinical applications

Leptin, an adipocyte-derived cytokine, crosses the blood–brain barrier to act on many regions of the central nervous system (CNS). It participates in the regulation of energy balance, inflammatory processes, immune regulation, synaptic formation, memory condensation, and neurotrophic activities. Thi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Weihong, Hsuchou, Hung, Jayaram, Bhavaani, Khan, Reas S, Huang, Eagle Yi-Kung, Wu, Xiaojun, Chen, Chu, Kastin, Abba J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Inc 2012
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407332/ https://www.ncbi.nlm.nih.gov/pubmed/22530983 http://dx.doi.org/10.1111/j.1749-6632.2012.06472.x

Ejemplares similares

Fibroblast growth factor 19 entry into brain
por: Hsuchou, Hung, et al.
Publicado: (2013)

TNF Stimulates Nuclear Export and Secretion of IL-15 by Acting on CRM1 and ARF6
por: Ouyang, Suidong, et al.
Publicado: (2013)

Brain Activation by Peptide Pro-Leu-Gly-NH(2) (MIF-1)
por: Khan, Reas S., et al.
Publicado: (2010)

Leukocyte infiltration across the blood-spinal cord barrier is modulated by sleep fragmentation in mice with experimental autoimmune encephalomyelitis
por: He, Junyun, et al.
Publicado: (2014)

Nonneuronal cells mediate neurotrophic action of vasoactive intestinal peptide
Publicado: (1987)

The role of nonneuronal neurotrophins in the brain
por: Čarman-Kržan, Marija
Publicado: (2009)

Overexpression of tau in a nonneuronal cell induces long cellular processes
Publicado: (1991)

VAMP/synaptobrevin isoforms 1 and 2 are widely and differentially expressed in nonneuronal tissues
Publicado: (1996)

Effect of Prolonged Moderate Exercise on the Changes of Nonneuronal Cells in Early Myocardial Infarction
por: Rinaldi, Barbara, et al.
Publicado: (2015)

Evolution, Expression, and Function of Nonneuronal Ligand-Gated Chloride Channels in Drosophila melanogaster
por: Remnant, Emily J., et al.
Publicado: (2016)

Embryonic Exposure to Dexamethasone Affects Nonneuronal Cells in the Adult Paraventricular Nucleus of the Hypothalamus
por: Frahm, Krystle A., et al.
Publicado: (2017)

Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection
Publicado: (1987)

Ascl1 (Mash1) Knockout Perturbs Differentiation of Nonneuronal Cells in Olfactory Epithelium
por: Krolewski, Richard C., et al.
Publicado: (2012)

Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments
Publicado: (1993)

Involvement of the Nonneuronal Cholinergic System in Bone Remodeling in Rat Midpalatal Suture after Rapid Maxillary Expansion
por: Che, Xiaoxia, et al.
Publicado: (2016)

A Functional Melanocortin System May Be Required for Chronic CNS-Mediated Antidiabetic and Cardiovascular Actions of Leptin
por: da Silva, Alexandre A., et al.
Publicado: (2009)

Treatment of chronic regional pain syndrome type 1 with palmitoylethanolamide and topical ketamine cream: modulation of nonneuronal cells
por: Keppel Hesselink, Jan M, et al.
Publicado: (2013)

Upregulating Nonneuronal Cholinergic Activity Decreases TNF Release from Lipopolysaccharide-Stimulated RAW264.7 Cells
por: Lv, Yi, et al.
Publicado: (2014)

The role of the Notch signalling pathway in regulating the balance between neuronal and nonneuronal cells in sympathetic ganglia and the adrenal gland
por: Shtukmaster, Stella, et al.
Publicado: (2023)

SIRT1 Activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease
por: Khan, Reas S, et al.
Publicado: (2014)

Phenotypic Resemblance to Neuropsychiatric Disorder and Altered mRNA Profiles in Cortex and Hippocampus Underlying IL15Rα Knockout
por: He, Yi, et al.
Publicado: (2021)

Reduced Serum Levels of Soluble Interleukin-15 Receptor α in Schizophrenia and Its Relationship to the Excited Phenotype
por: He, Yi, et al.
Publicado: (2022)

Endogenous opiates: 1993
por: Olson, Gayle A., et al.
Publicado: (1994)

The glucoregulatory actions of leptin
por: D'souza, Anna M., et al.
Publicado: (2017)

Expression of NF-L in both neuronal and nonneuronal cells of transgenic mice: increased neurofilament density in axons without affecting caliber
Publicado: (1990)

Leptin action in normal and pathological pregnancies
por: Pérez‐Pérez, Antonio, et al.
Publicado: (2017)

Leptin and its actions on reproduction in males
por: Malik, Ifrah Alam, et al.
Publicado: (2019)

Transcriptional and physiological roles for STAT proteins in leptin action
por: Pan, Warren, et al.
Publicado: (2019)

Novel Regulatory Mechanisms for Generation of the Soluble Leptin Receptor: Implications for Leptin Action
por: Schaab, Michael, et al.
Publicado: (2012)

Increased Phagocyte-Like NADPH Oxidase and ROS Generation in Type 2 Diabetic ZDF Rat and Human Islets: Role of Rac1–JNK1/2 Signaling Pathway in Mitochondrial Dysregulation in the Diabetic Islet
por: Syed, Ismail, et al.
Publicado: (2011)

Electroacupuncture Reduces Weight Gain Induced by Rosiglitazone through PPARγ and Leptin Receptor in CNS
por: Jing, Xinyue, et al.
Publicado: (2016)

Fyn Mediates Leptin Actions in the Thymus of Rodents
por: Girasol, Alessandra, et al.
Publicado: (2009)

Interaction of glucose sensing and leptin action in the brain
por: Li, Rosa J.W., et al.
Publicado: (2020)

VPAC1 receptor (Vipr1)-deficient mice exhibit ameliorated experimental autoimmune encephalomyelitis, with specific deficits in the effector stage
por: Abad, Catalina, et al.
Publicado: (2016)

Erratum to: VPAC1 receptor (Vipr1)-deficient mice exhibit ameliorated experimental autoimmune encephalomyelitis, with specific deficits in the effector stage
por: Abad, Catalina, et al.
Publicado: (2017)

Insufficiency of Janus Kinase 2–Autonomous Leptin Receptor Signals for Most Physiologic Leptin Actions
por: Robertson, Scott, et al.
Publicado: (2010)

Restoration of Cardiac Function After Myocardial Infarction by Long-Term Activation of the CNS Leptin-Melanocortin System
por: Gava, Fabio N., et al.
Publicado: (2021)

Leptin-Activity Modulators and Their Potential Pharmaceutical Applications
por: Greco, Marianna, et al.
Publicado: (2021)

Chemokine Actions in the CNS: Insights from Transgenic Mice
por: Müller, Marcus, et al.
Publicado: (2008)

Human IL6 enhances leptin action in mice
por: Sadagurski, M., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_qskjcunbsfv7s8m99v078mlhca