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Increasing levels of wild-type CREB up-regulates several activity-regulated inhibitor of death (AID) genes and promotes neuronal survival

BACKGROUND: CREB (cAMP-response element binding protein) is the prototypical signal-regulated transcription factor. In neurons, it is the target of the synaptic activity-induced nuclear calcium-calcium/calmodulin dependent protein kinase (CaMK) IV signaling pathway that controls the expression of ge...

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Detalles Bibliográficos
Autores principales: Tan, Yan-Wei, Hoffmann, Tina, Bading, Hilmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407521/
https://www.ncbi.nlm.nih.gov/pubmed/22607375
http://dx.doi.org/10.1186/1471-2202-13-48