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Comparison of Gene Expression Profiling in Sarcomas and Mesenchymal Stem Cells Identifies Tumorigenic Pathways in Chemically Induced Rat Sarcoma Model

Mesenchymal stem cells (MSCs) are believed to be the cell of origin for most sarcomas including osteosarcoma and malignant fibrous histiocytoma (MFH/UPS). To identify the signaling pathways involved in sarcoma pathogenesis, we compared gene expression profiles in rat osteosarcoma and MFH cells with...

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Detalles Bibliográficos
Autores principales: Honoki, Kanya, Fujii, Hiromasa, Tohma, Yasuaki, Tsujiuchi, Toshifumi, Kido, Akira, Tsukamoto, Shinji, Mori, Toshio, Tanaka, Yasuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407640/
https://www.ncbi.nlm.nih.gov/pubmed/22852096
http://dx.doi.org/10.5402/2012/909453

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