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Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome

Mesenchymal stem cells (MSCs) are used in many of the current stem cell-based clinical trials and their therapeutic efficacy has increasingly been attributed to secretion of paracrine factors. We have previously demonstrated that a therapeutic constituent of this secretion is exosome, a secreted bil...

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Detalles Bibliográficos
Autores principales: Lai, Ruenn Chai, Tan, Soon Sim, Teh, Bao Ju, Sze, Siu Kwan, Arslan, Fatih, de Kleijn, Dominique P., Choo, Andre, Lim, Sai Kiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407643/
https://www.ncbi.nlm.nih.gov/pubmed/22852084
http://dx.doi.org/10.1155/2012/971907