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Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome
Mesenchymal stem cells (MSCs) are used in many of the current stem cell-based clinical trials and their therapeutic efficacy has increasingly been attributed to secretion of paracrine factors. We have previously demonstrated that a therapeutic constituent of this secretion is exosome, a secreted bil...
Autores principales: | Lai, Ruenn Chai, Tan, Soon Sim, Teh, Bao Ju, Sze, Siu Kwan, Arslan, Fatih, de Kleijn, Dominique P., Choo, Andre, Lim, Sai Kiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407643/ https://www.ncbi.nlm.nih.gov/pubmed/22852084 http://dx.doi.org/10.1155/2012/971907 |
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