Dysregulation of the Autophagy-Endolysosomal System in Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases

Amyotrophic lateral sclerosis (ALS) is a heterogeneous group of incurable motor neuron diseases (MNDs) characterized by a selective loss of upper and lower motor neurons in the brain and spinal cord. Most cases of ALS are sporadic, while approximately 5–10% cases are familial. More than 16 causative...

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Detalles Bibliográficos
Autores principales: Otomo, Asako, Pan, Lei, Hadano, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407648/
https://www.ncbi.nlm.nih.gov/pubmed/22852081
http://dx.doi.org/10.1155/2012/498428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407648/
https://www.ncbi.nlm.nih.gov/pubmed/22852081
http://dx.doi.org/10.1155/2012/498428

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