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NPM-ALK: The Prototypic Member of a Family of Oncogenic Fusion Tyrosine Kinases
Anaplastic lymphoma kinase (ALK) was first identified in 1994 with the discovery that the gene encoding for this kinase was involved in the t(2;5)(p23;q35) chromosomal translocation observed in a subset of anaplastic large cell lymphoma (ALCL). The NPM-ALK fusion protein generated by this translocat...
Autores principales: | Pearson, Joel D., Lee, Jason K. H., Bacani, Julinor T. C., Lai, Raymond, Ingham, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407651/ https://www.ncbi.nlm.nih.gov/pubmed/22852078 http://dx.doi.org/10.1155/2012/123253 |
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