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Direct interaction between GluR2 and GAPDH regulates AMPAR-mediated excitotoxicity

Over-activation of AMPARs (α−amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype glutamate receptors) is implicated in excitotoxic neuronal death associated with acute brain insults, such as ischemic stroke. However, the specific molecular mechanism by which AMPARs, especially the calcium-imp...

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Detalles Bibliográficos
Autores principales:	Wang, Min, Li, Shupeng, Zhang, Hongyu, Pei, Lin, Zou, Shengwei, Lee, Frank J S, Wang, Yu Tian, Liu, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407747/ https://www.ncbi.nlm.nih.gov/pubmed/22537872 http://dx.doi.org/10.1186/1756-6606-5-13

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