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Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications
Conjugation of ubiquitin to proteins (ubiquitylation) has emerged to be one of the most crucial post-translational modifications controlling virtually all cellular processes. What was once regarded as a mere signal for protein degradation has turned out to be a major regulator of molecular signallin...
Autores principales: | Fulda, Simone, Rajalingam, Krishnaraj, Dikic, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407942/ https://www.ncbi.nlm.nih.gov/pubmed/22730341 http://dx.doi.org/10.1002/emmm.201100707 |
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