Proline-Rich Tyrosine Kinase 2 (Pyk2) Regulates IGF-I-Induced Cell Motility and Invasion of Urothelial Carcinoma Cells

The insulin-like growth factor receptor I (IGF-IR) plays an essential role in transformation by promoting cell growth and protecting cancer cells from apoptosis. We have recently demonstrated that the IGF-IR is overexpressed in invasive bladder cancer tissues and promotes motility and invasion of ur...

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Detalles Bibliográficos
Autores principales: Genua, Marco, Xu, Shi-Qiong, Buraschi, Simone, Peiper, Stephen C., Gomella, Leonard G., Belfiore, Antonino, Iozzo, Renato V., Morrione, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408023/
https://www.ncbi.nlm.nih.gov/pubmed/22859931
http://dx.doi.org/10.1371/journal.pone.0040148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408023/
https://www.ncbi.nlm.nih.gov/pubmed/22859931
http://dx.doi.org/10.1371/journal.pone.0040148

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