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Small Molecule-Assisted, Line-Independent Maintenance of Human Pluripotent Stem Cells in Defined Conditions
Human pluripotent stem cells (hPSCs) are conventionally grown in a mouse feeder cell-dependent manner. Chemically defined culture conditions are, however, desirable not only for potential medically oriented applications but also for investigating mechanisms of self-renewal and differentiation. In li...
Autores principales: | Frank, Stefan, Zhang, Miao, Schöler, Hans R., Greber, Boris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408405/ https://www.ncbi.nlm.nih.gov/pubmed/22860038 http://dx.doi.org/10.1371/journal.pone.0041958 |
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