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The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation
Leukocyte transendothelial migration involves the active participation of the endothelium through the formation of apical membrane protrusions that embrace adherent leukocytes, termed docking structures. Using live-cell imaging, we find that prior to transmigration, endothelial docking structures fo...
Autores principales: | van Rijssel, Jos, Kroon, Jeffrey, Hoogenboezem, Mark, van Alphen, Floris P. J., de Jong, Renske J., Kostadinova, Elena, Geerts, Dirk, Hordijk, Peter L., van Buul, Jaap D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408411/ https://www.ncbi.nlm.nih.gov/pubmed/22696684 http://dx.doi.org/10.1091/mbc.E11-11-0907 |
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