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Fission yeast Alp14 is a dose-dependent plus end–tracking microtubule polymerase

XMAP215/Dis1 proteins are conserved tubulin-binding TOG-domain proteins that regulate microtubule (MT) plus-end dynamics. Here we show that Alp14, a XMAP215 orthologue in fission yeast, Schizosaccharomyces pombe, has properties of a MT polymerase. In vivo, Alp14 localizes to growing MT plus ends in...

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Detalles Bibliográficos
Autores principales:	Al-Bassam, Jawdat, Kim, Hwajin, Flor-Parra, Ignacio, Lal, Neeraj, Velji, Hamida, Chang, Fred
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408415/ https://www.ncbi.nlm.nih.gov/pubmed/22696680 http://dx.doi.org/10.1091/mbc.E12-03-0205

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