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Stimulation of Wnt/ß-Catenin Pathway in Human CD8(+) T Lymphocytes from Blood and Lung Tumors Leads to a Shared Young/Memory Phenotype
Cancer can be treated by adoptive cell transfer (ACT) of T lymphocytes. However, how to optimally raise human T cells to a differentiation state allowing the best persistence in ACT is a challenge. It is possible to differentiate mouse CD8(+) T cells towards stem cell-like memory (T(SCM)) phenotype...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408435/ https://www.ncbi.nlm.nih.gov/pubmed/22859966 http://dx.doi.org/10.1371/journal.pone.0041074 |