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Withaferin A Synergizes the Therapeutic Effect of Doxorubicin through ROS-Mediated Autophagy in Ovarian Cancer
Application of doxorubicin (Dox) for the treatment of cancer is restricted due to its severe side effects. We used combination strategy by combining doxorubicin (Dox) with withaferin A (WFA) to minimize the ill effects of Dox. Treatment of various epithelial ovarian cancer cell lines (A2780, A2780/C...
Autores principales: | Fong, Miranda Y., Jin, Shunying, Rane, Madhavi, Singh, Raj K., Gupta, Ramesh, Kakar, Sham S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408484/ https://www.ncbi.nlm.nih.gov/pubmed/22860102 http://dx.doi.org/10.1371/journal.pone.0042265 |
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