Depletion of c-Rel from Cytokine Gene Promoters Is Required for Chromatin Reassembly and Termination of Gene Responses to T Cell Activation

The role of the Nuclear Factor κB (NF-κB) transcription factor family in T cell function has been well described. The c-Rel family member is of particular importance in initiating T cell responses to antigen and regulating activation of inflammatory cytokine genes, including the Interleukin-2 (IL-2)...

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Detalles Bibliográficos
Autores principales: Poke, Fiona S., Upcher, William R., Sprod, Owen R., Young, Arabella, Brettingham-Moore, Kate H., Holloway, Adele F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408492/
https://www.ncbi.nlm.nih.gov/pubmed/22860011
http://dx.doi.org/10.1371/journal.pone.0041734

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