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Rapid One-Step Selection Method for Generating Nucleic Acid Aptamers: Development of a DNA Aptamer against α-Bungarotoxin

BACKGROUND: Nucleic acids based therapeutic approaches have gained significant interest in recent years towards the development of therapeutics against many diseases. Recently, research on aptamers led to the marketing of Macugen®, an inhibitor of vascular endothelial growth factor (VEGF) for the tr...

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Detalles Bibliográficos
Autores principales: Lauridsen, Lasse H., Shamaileh, Hadi A., Edwards, Stacey L., Taran, Elena, Veedu, Rakesh N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408503/
https://www.ncbi.nlm.nih.gov/pubmed/22860007
http://dx.doi.org/10.1371/journal.pone.0041702

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