RNA sequencing of pancreatic circulating tumour cells implicates WNT signaling in metastasis

Circulating tumour cells (CTCs) shed into blood from primary cancers include putative precursors that initiate distal metastases(1). While these cells are extraordinarily rare, they may identify cellular pathways contributing to the blood-borne dissemination of cancer. Here, we adapted a microfluidi...

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Detalles Bibliográficos
Autores principales: Yu, Min, Ting, David T., Stott, Shannon L., Wittner, Ben S., Ozsolak, Fatih, Paul, Suchismita, Ciciliano, Jordan C., Smas, Malgorzata E., Winokur, Daniel, Gilman, Anna J., Ulman, Matthew J., Xega, Kristina, Contino, Gianmarco, Alagesan, Brinda, Brannigan, Brian W., Milos, Patrice M., Ryan, David P, Sequist, Lecia V., Bardeesy, Nabeel, Ramaswamy, Sridhar, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408856/
https://www.ncbi.nlm.nih.gov/pubmed/22763454
http://dx.doi.org/10.1038/nature11217

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