Cargando…
Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α
Following acute hepatic injury, the metabolic capacity of the liver is altered during the process of compensatory hepatocyte proliferation by undefined mechanisms. In this study, we examined the regulation of de novo lipogenesis by cyclin D1, a key mediator of hepatocyte cell cycle progression. In p...
Autores principales: | Hanse, Eric A., Mashek, Douglas G., Becker, Jennifer R., Solmonson, Ashley D., Mullany, Lisa K., Mashek, Mara T., Towle, Howard C., Chau, Anhtung T., Albrecht, Jeffrey H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409010/ https://www.ncbi.nlm.nih.gov/pubmed/22751438 http://dx.doi.org/10.4161/cc.21019 |
Ejemplares similares
-
Cyclin D1 represses peroxisome proliferator-activated receptor alpha and inhibits fatty acid oxidation
por: Kamarajugadda, Sushama, et al.
Publicado: (2016) -
Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes
por: Wu, Heng, et al.
Publicado: (2019) -
ACOT1 deficiency attenuates high-fat diet–induced fat mass gain by increasing energy expenditure
por: Heden, Timothy D., et al.
Publicado: (2023) -
ATGL-Catalyzed Lipolysis Regulates SIRT1 to Control PGC-1α/PPAR-α Signaling
por: Khan, Salmaan Ahmed, et al.
Publicado: (2015) -
Hepatic lipid droplets: A balancing act between energy storage and metabolic dysfunction in NAFLD
por: Mashek, Douglas G.
Publicado: (2020)