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Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice

BACKGROUND: The striato-nigral projecting pathway contains the highest concentrations of dynorphin in the brain. The functional role of this opioid peptide in the regulation of mesencephalic dopaminergic (DAergic) neurons is not clear. We reported previously that exogenous dynorphin exerts potent ne...

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Detalles Bibliográficos
Autores principales:	Wang, Qingshan, Shin, Eun-Joo, Nguyen, Xuan-Khanh Thi, Li, Quan, Bach, Jae-Hyung, Bing, Guoying, Kim, Won-Ki, Kim, Hyoung-Chun, Hong, Jau-Shyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409049/ https://www.ncbi.nlm.nih.gov/pubmed/22695044 http://dx.doi.org/10.1186/1742-2094-9-124

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