A single cidofovir treatment rescues animals at progressive stages of lethal orthopoxvirus disease

BACKGROUND: In an event of a smallpox outbreak in humans, the window for efficacious treatment by vaccination with vaccinia viruses (VACV) is believed to be limited to the first few days post-exposure (p.e.). We recently demonstrated in a mouse model for human smallpox, that active immunization 2–3 ...

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Detalles Bibliográficos
Autores principales: Israely, Tomer, Paran, Nir, Lustig, Shlomo, Erez, Noam, Politi, Boaz, Shafferman, Avigdor, Melamed, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409050/
https://www.ncbi.nlm.nih.gov/pubmed/22709563
http://dx.doi.org/10.1186/1743-422X-9-119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409050/
https://www.ncbi.nlm.nih.gov/pubmed/22709563
http://dx.doi.org/10.1186/1743-422X-9-119

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