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A single cidofovir treatment rescues animals at progressive stages of lethal orthopoxvirus disease
BACKGROUND: In an event of a smallpox outbreak in humans, the window for efficacious treatment by vaccination with vaccinia viruses (VACV) is believed to be limited to the first few days post-exposure (p.e.). We recently demonstrated in a mouse model for human smallpox, that active immunization 2–3 ...
Autores principales: | Israely, Tomer, Paran, Nir, Lustig, Shlomo, Erez, Noam, Politi, Boaz, Shafferman, Avigdor, Melamed, Sharon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409050/ https://www.ncbi.nlm.nih.gov/pubmed/22709563 http://dx.doi.org/10.1186/1743-422X-9-119 |
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