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Relative transmembrane segment rearrangements during BK channel activation resolved by structurally assigned fluorophore–quencher pairing
Voltage-activated proteins can sense, and respond to, changes in the electric field pervading the cell membrane by virtue of a transmembrane helix bundle, the voltage-sensing domain (VSD). Canonical VSDs consist of four transmembrane helices (S1–S4) of which S4 is considered a principal component be...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409098/ https://www.ncbi.nlm.nih.gov/pubmed/22802360 http://dx.doi.org/10.1085/jgp.201210807 |