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Luminal Ca(2+) controls activation of the cardiac ryanodine receptor by ATP

The synergic effect of luminal Ca(2+), cytosolic Ca(2+), and cytosolic adenosine triphosphate (ATP) on activation of cardiac ryanodine receptor (RYR2) channels was examined in planar lipid bilayers. The dose–response of RYR2 gating activity to ATP was characterized at a diastolic cytosolic Ca(2+) co...

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Detalles Bibliográficos
Autores principales: Tencerová, Barbora, Zahradníková, Alexandra, Gaburjáková, Jana, Gaburjáková, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409101/
https://www.ncbi.nlm.nih.gov/pubmed/22851674
http://dx.doi.org/10.1085/jgp.201110708

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