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Activation of Indoleamine 2,3-Dioxygenase in Patients with Scrub Typhus and Its Role in Growth Restriction of Orientia tsutsugamushi

BACKGROUND: Our earlier genome-wide expression study revealed up-regulation of a tryptophan-catabolizing enzyme, indoleamine 2,3-dioxygenase (IDO1), in patients with scrub typhus. This gene has been previously reported to have anti-microbial activity in a variety of infectious diseases; therefore, w...

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Detalles Bibliográficos
Autores principales:	Prachason, Thanavadee, Konhan, Kanittha, Pongnarin, Piyapat, Chatsiricharoenkul, Somruedee, Suputtamongkol, Yupin, Limwongse, Chanin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409113/ https://www.ncbi.nlm.nih.gov/pubmed/22860140 http://dx.doi.org/10.1371/journal.pntd.0001731

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