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Diverse Inhibitor Chemotypes Targeting Trypanosoma cruzi CYP51
BACKGROUND: Chagas Disease, a WHO- and NIH-designated neglected tropical disease, is endemic in Latin America and an emerging infection in North America and Europe as a result of population moves. Although a major cause of morbidity and mortality due to heart failure, as well as inflicting a heavy e...
Autores principales: | Gunatilleke, Shamila S., Calvet, Claudia M., Johnston, Jonathan B., Chen, Chiung-Kuang, Erenburg, Grigori, Gut, Jiri, Engel, Juan C., Ang, Kenny K. H., Mulvaney, Joseph, Chen, Steven, Arkin, Michelle R., McKerrow, James H., Podust, Larissa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409115/ https://www.ncbi.nlm.nih.gov/pubmed/22860142 http://dx.doi.org/10.1371/journal.pntd.0001736 |
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