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The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi

Malaria vaccine developers are concerned that antigenic escape will erode vaccine efficacy. Evolutionary theorists have raised the possibility that some types of vaccine could also create conditions favoring the evolution of more virulent pathogens. Such evolution would put unvaccinated people at gr...

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Detalles Bibliográficos
Autores principales: Barclay, Victoria C., Sim, Derek, Chan, Brian H. K., Nell, Lucas A., Rabaa, Maia A., Bell, Andrew S., Anders, Robin F., Read, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409122/
https://www.ncbi.nlm.nih.gov/pubmed/22870063
http://dx.doi.org/10.1371/journal.pbio.1001368

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