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The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi
Malaria vaccine developers are concerned that antigenic escape will erode vaccine efficacy. Evolutionary theorists have raised the possibility that some types of vaccine could also create conditions favoring the evolution of more virulent pathogens. Such evolution would put unvaccinated people at gr...
Autores principales: | Barclay, Victoria C., Sim, Derek, Chan, Brian H. K., Nell, Lucas A., Rabaa, Maia A., Bell, Andrew S., Anders, Robin F., Read, Andrew F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409122/ https://www.ncbi.nlm.nih.gov/pubmed/22870063 http://dx.doi.org/10.1371/journal.pbio.1001368 |
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