Expression of PPARγ and Paraoxonase 2 Correlated with Pseudomonas aeruginosa Infection in Cystic Fibrosis

The Pseudomonas aeruginosa quorum sensing signal molecule N-3-oxododecanoyl-l-homoserine lactone (3OC(12)HSL) can inhibit function of the mammalian anti-inflammatory transcription factor peroxisome proliferator activated receptor (PPAR)γ, and can be degraded by human paraoxonase (PON)2. Because 3OC(...

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Detalles Bibliográficos
Autores principales: Griffin, Phoebe E., Roddam, Louise F., Belessis, Yvonne C., Strachan, Roxanne, Beggs, Sean, Jaffe, Adam, Cooley, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409144/
https://www.ncbi.nlm.nih.gov/pubmed/22860094
http://dx.doi.org/10.1371/journal.pone.0042241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409144/
https://www.ncbi.nlm.nih.gov/pubmed/22860094
http://dx.doi.org/10.1371/journal.pone.0042241

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