Warburg Effect’s Manifestation in Aggressive Pheochromocytomas and Paragangliomas: Insights from a Mouse Cell Model Applied to Human Tumor Tissue

A glycolytic profile unifies a group of pheochromocytomas and paragangliomas (PHEOs/PGLs) with distinct underlying gene defects, including von Hippel-Lindau (VHL) and succinate dehydrogenase B (SDHB) mutations. Nevertheless, their tumor aggressiveness is distinct: PHEOs/PGLs metastasize rarely in VH...

Descripción completa

Detalles Bibliográficos
Autores principales: Fliedner, Stephanie M. J., Kaludercic, Nina, Jiang, Xiao-Sheng, Hansikova, Hana, Hajkova, Zuzana, Sladkova, Jana, Limpuangthip, Andrea, Backlund, Peter S., Wesley, Robert, Martiniova, Lucia, Jochmanova, Ivana, Lendvai, Nikoletta K., Breza, Jan, Yergey, Alfred L., Paolocci, Nazareno, Tischler, Arthur S., Zeman, Jiri, Porter, Forbes D., Lehnert, Hendrik, Pacak, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409208/
https://www.ncbi.nlm.nih.gov/pubmed/22859959
http://dx.doi.org/10.1371/journal.pone.0040949

Ejemplares similares

Ejemplares similares