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Regulation of Nuclear Factor κB (NF-κB) Transcriptional Activity via p65 Acetylation by the Chaperonin Containing TCP1 (CCT)

The NF-κB family member p65 is central to inflammation and immunity. The purpose of this study was to identify and characterize evolutionary conserved genes modulating p65 transcriptional activity. Using an RNAi screening approach, we identified chaperonin containing TCP1 subunit η (CCTη) as a regul...

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Detalles Bibliográficos
Autores principales: Pejanovic, Nadja, Hochrainer, Karin, Liu, Tao, Aerne, Birgit L., Soares, Miguel P., Anrather, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409233/
https://www.ncbi.nlm.nih.gov/pubmed/22860050
http://dx.doi.org/10.1371/journal.pone.0042020