A behavioral weight loss intervention for persons with serious mental illness in psychiatric rehabilitation centers

OBJECTIVE: Overweight and obesity are epidemic in populations with serious mental illnesses. We developed and pilot tested a behavioral weight loss intervention appropriately tailored for persons with serious mental disorders. METHODS: We conducted a single arm pilot study in two psychiatric rehabilitation day programs in Maryland and enrolled 63 overweight or obese adults. The six-month intervention provided group and individual weight management and group physical activity classes. The primary outcome was weight change from baseline to 6 months. RESULTS: Sixty-four percent of those potentially eligible at the centers enrolled. The mean age was 43.7 years; 56% were women, 49% were white and over half had a schizophrenia or schizoaffective disorder. One third had hypertension and one fifth had diabetes. Fifty-two (82%) completed the study; others were discharged from psychiatric centers before study completion. Average attendance across all weight management sessions was 70% (87% on days participants attended the center) and 59% for physical activity classes (74% on days participants attended the center). From a baseline mean of 210.9 lbs (SD 43.9), average weight loss for 52 participants was 4.5 pounds (SD 12.8) (p<0.014). On average, participants lost 1.9% of body weight. Mean waist circumference change was 3.1 cm (SD 5.6). Participants on average increased the distance on the six minute walk test by eight percent. CONCLUSION: This pilot documents the feasibility and preliminary efficacy of a behavioral weight loss intervention in adults with serious mental illness who were attendees at psychiatric rehabilitation centers. The results may have implications for developing weight loss interventions in other institutional settings such as schools or nursing homes.