Adenosine deaminases that act on RNA induce reproducible changes in abundance and sequence of embryonic miRNAs

Adenosine deaminases that act on RNA bind double-stranded and structured RNAs and convert adenosines to inosines by hydrolytic deamination. Inosines are recognized as guanosines, and, hence, RNA editing alters the sequence information but also structure of RNAs. Editing by ADARs is widespread and es...

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Detalles Bibliográficos
Autores principales: Vesely, Cornelia, Tauber, Stefanie, Sedlazeck, Fritz J., von Haeseler, Arndt, Jantsch, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409260/
https://www.ncbi.nlm.nih.gov/pubmed/22310477
http://dx.doi.org/10.1101/gr.133025.111

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